rs121913529, KRAS

N. diseases: 144
Disease: Pancreatic intraepithelial neoplasia ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Pancreatic intraepithelial neoplasia
CUI: C1301034
Disease: Pancreatic intraepithelial neoplasia
0.030 GeneticVariation BEFREE Klf4 ablation drastically attenuates the formation of pancreatic intraepithelial neoplasia induced by mutant Kras(G12D), whereas upregulation of KLF4 does the opposite. 26977883 2016
Pancreatic intraepithelial neoplasia
CUI: C1301034
Disease: Pancreatic intraepithelial neoplasia
0.030 GeneticVariation BEFREE Most notably, the early development of pancreatic intraepithelial neoplasia and lung lesions is suggested to be the result of a mutation in the K-ras (G12D) oncogene. 20848283 2011
Pancreatic intraepithelial neoplasia
CUI: C1301034
Disease: Pancreatic intraepithelial neoplasia
0.030 GeneticVariation BEFREE Delayed progression of pancreatic intraepithelial neoplasia in a conditional Kras(G12D) mouse model by a selective cyclooxygenase-2 inhibitor. 17652141 2007