rs1260326, GCKR

N. diseases: 81
Disease: Hypertriglyceridemia ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Hypertriglyceridemia
CUI: C0020557
Disease: Hypertriglyceridemia
0.820 GeneticVariation BEFREE Once demographics, medication use and baseline adiposity, and fitness were accounted for, ILI did not modify the baseline association of GCKR-Leu446Pro with elevated triglycerides (β±SE=0.067±0.013, P=1.5×10(-7) and β±SE=0.052±0.015, P=5×10(-4)) or with elevated CRP (β±SE=0.136±0.034, P=5.1×10(-5)and β±SE=0.903±0.038, P=0.015) in the overall sample and Non-Hispanic Whites, respectively. 26578543 2016
Hypertriglyceridemia
CUI: C0020557
Disease: Hypertriglyceridemia
0.820 GeneticVariation GWASDB Genomic study in Mexicans identifies a new locus for triglycerides and refines European lipid loci. 23505323 2013
Hypertriglyceridemia
CUI: C0020557
Disease: Hypertriglyceridemia
0.820 GeneticVariation BEFREE Recently, the single nucleotide polymorphism (SNP) identified as rs1260326, in the glucokinase regulatory protein (GCKR), was associated with hypertriglyceridemia in adults. 22105854 2012
Hypertriglyceridemia
CUI: C0020557
Disease: Hypertriglyceridemia
0.820 GeneticVariation GWASDB Excess of rare variants in genes identified by genome-wide association study of hypertriglyceridemia. 20657596 2010
Hypertriglyceridemia
CUI: C0020557
Disease: Hypertriglyceridemia
0.820 GeneticVariation GWASCAT Excess of rare variants in genes identified by genome-wide association study of hypertriglyceridemia. 20657596 2010