Bipolar Disorder
|
|
0.100 |
GeneticVariation
|
BEFREE |
In model 2, ZNF804A rs1344706 was significantly associated with BD; however, this association did not predict diagnosis when entered into the weighted model.
|
31727397 |
2020 |
Bipolar Disorder
|
|
0.100 |
GeneticVariation
|
BEFREE |
CACNA1C-rs1006737 and ZNF804A-rs1344706 polymorphisms are among the most robustly associated with schizophrenia (SCZ) and bipolar disorder (BD), and recently with brain phenotypes.
|
30079586 |
2019 |
Bipolar Disorder
|
|
0.100 |
GeneticVariation
|
BEFREE |
Meta-analysis of rs1344706 by pooling all available data showed that rs1344706 was significantly associated with BD (P = 0.001).
|
28120939 |
2017 |
Bipolar Disorder
|
|
0.100 |
GeneticVariation
|
BEFREE |
Genome-wide studies have identified allele A (adenine) of single nucleotide polymorphism (SNP) rs1006737 of the calcium-channel CACNA1C gene as a risk factor for both schizophrenia (SZ) and bipolar disorder (BD) as well as allele A for rs1344706 in the ZNF804A gene.
|
27790829 |
2017 |
Bipolar Disorder
|
|
0.100 |
GeneticVariation
|
BEFREE |
The European GWAS risk single nucleotide polymorphism (SNP) rs1344706 was nominally associated with schizophrenia in these Asian samples (one-tailed P = 4.26 × 10(-2) , odds ratio [OR] = 1.048), and the association was further strengthened when bipolar disorder data was also included (one-tailed P = 1.85 × 10(-2) , OR = 1.057).
|
26866941 |
2016 |
Bipolar Disorder
|
|
0.100 |
GeneticVariation
|
BEFREE |
Here, we review literature recently published on ZNF804A, and analyze critical concepts related to the biology of ZNF804A and the role of rs1344706 in schizophrenia and bipolar disorder.
|
25522715 |
2015 |
Bipolar Disorder
|
|
0.100 |
GeneticVariation
|
BEFREE |
While no significant association between rs1344706 and SZ or BD was observed in the Costa Rica sample, we observed an increased risk of SZ for the minor allele (A) of the exonic rs12476147 SNP (p=0.026).
|
24315717 |
2014 |
Bipolar Disorder
|
|
0.100 |
GeneticVariation
|
BEFREE |
The rs1344706 single nucleotide polymorphism within intron 2 of the ZNF804A gene is strongly associated with schizophrenia and bipolar disorder.
|
24636489 |
2014 |
Bipolar Disorder
|
|
0.100 |
GeneticVariation
|
BEFREE |
The single-nucleotide polymorphism rs1344706 in the zinc finger protein 804A gene (ZNF804A) shows genome-wide association with schizophrenia and bipolar disorder.
|
25162540 |
2014 |
Bipolar Disorder
|
|
0.100 |
GeneticVariation
|
BEFREE |
Genome-wide association studies have provided strong evidence for association of the SNP rs1344706 in the ZNF804A gene with schizophrenia and bipolar disorder.
|
24685285 |
2014 |
Bipolar Disorder
|
|
0.100 |
GeneticVariation
|
BEFREE |
ZNF804A SNP rs1344706 confers genome-wide risk for schizophrenia and bipolar disorder.
|
23562677 |
2013 |
Bipolar Disorder
|
|
0.100 |
GeneticVariation
|
BEFREE |
Genome-wide association studies identified the single nucleotide polymorphism rs1344706 in ZNF804A as a common risk-variant for schizophrenia and bipolar disorder.
|
22042765 |
2013 |
Bipolar Disorder
|
|
0.100 |
GeneticVariation
|
BEFREE |
The ZNF804A rs1344706 variant was the first risk factor to be identified through genome-wide association studies and follow-up studies with meta-analysis for schizophrenia as well as bipolar disorders; we investigated 231 schizophrenia and 222 controls to see whether this particular variant was associated with schizophrenia in a Romanian population from Cluj Napoca.
|
22775511 |
2012 |
Bipolar Disorder
|
|
0.100 |
GeneticVariation
|
BEFREE |
Follow-up studies involving meta-analysis have confirmed that rs1344706 is a risk factor for schizophrenia as well as bipolar disorders.
|
21988329 |
2012 |
Bipolar Disorder
|
|
0.100 |
GeneticVariation
|
BEFREE |
The meta-analysis provided evidence for association between rs1344706 that surpasses widely accepted benchmarks of significance by several orders of magnitude for both schizophrenia (P=2.5 × 10(-11), odds ratio (OR) 1.10, 95% confidence interval 1.07-1.14) and schizophrenia and bipolar disorder combined (P=4.1 × 10(-13), OR 1.11, 95% confidence interval 1.07-1.14).
|
20368704 |
2011 |