rs17125721, PSEN1

N. diseases: 14
Disease: Mental deterioration ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Mental deterioration
CUI: C0234985
Disease: Mental deterioration
0.020 GeneticVariation BEFREE Additionally, we found that in the presence of at least one APOE-ε4 allele, p.E318G is associated with more Aβ plaques and faster cognitive decline. 23990795 2013
Mental deterioration
CUI: C0234985
Disease: Mental deterioration
0.020 GeneticVariation BEFREE Follow-up studies should clarify whether the Glu318Gly mutation increases the risk of cognitive decline in later life. 11755019 2002