rs1799983, NOS3

N. diseases: 246
Disease: Metabolic Syndrome X ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Metabolic Syndrome X
CUI: C0524620
Disease: Metabolic Syndrome X
0.080 GeneticVariation BEFREE In addition, the haplotypes composed of G894T and C774T polymorphisms are associated with the MetS susceptibility in Russian population. 29907847 2018
Metabolic Syndrome X
CUI: C0524620
Disease: Metabolic Syndrome X
0.080 GeneticVariation BEFREE We investigated whether genetic polymorphisms in the endothelial nitric oxide (eNOS) gene (T(786)C in the promoter region, Glu298Asp in exon 7, and 4b/4a in intron 4) or eNOS haplotypes are associated with metabolic syndrome (MetS) in obese children and adolescents. 22983816 2013
Metabolic Syndrome X
CUI: C0524620
Disease: Metabolic Syndrome X
0.080 GeneticVariation BEFREE We investigated the role of three NOS3 polymorphisms (T-786C, intron 4b/a, and G894T) in the risk of MetS using a hospital-based case-control study. 23324585 2013
Metabolic Syndrome X
CUI: C0524620
Disease: Metabolic Syndrome X
0.080 GeneticVariation BEFREE The association of eNOS G894T polymorphism with metabolic syndrome and erectile dysfunction. 22304542 2012
Metabolic Syndrome X
CUI: C0524620
Disease: Metabolic Syndrome X
0.080 GeneticVariation BEFREE NOS3 Glu298Asp polymorphism interacts with virgin olive oil phenols to determine the postprandial endothelial function in patients with the metabolic syndrome. 21816783 2011
Metabolic Syndrome X
CUI: C0524620
Disease: Metabolic Syndrome X
0.080 GeneticVariation BEFREE We found that genotype Met/Met of the Val66Met polymorphism of the brain-derived neurotrophic factor gene was positively associated with depressive disorder (P < 0.05), but we were not able to find any significant associations of both the depressive disorder and metabolic syndrome with the remaining polymorphisms studied (methylenetetrahydrofolate reductase 677CT, methylenetet rahydrofolate reductase 1298AC, endothelial nitric oxide synthase Glu298Asp, and tyrosine hydroxylase). 20163778 2010
Metabolic Syndrome X
CUI: C0524620
Disease: Metabolic Syndrome X
0.080 GeneticVariation BEFREE Our data suggests that 894G>T plays a significant role in the mechanistic interaction between metabolic risk such as hypertension and MS, although sex-related differences may exist. 19169496 2008
Metabolic Syndrome X
CUI: C0524620
Disease: Metabolic Syndrome X
0.080 GeneticVariation BEFREE This study shows that, in a Chinese population, eNOS G894T polymorphism is associated with an elevated C-reactive protein level and MS. 18640391 2008