rs1801483, GCGR

N. diseases: 7
Disease: Essential Hypertension ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Essential Hypertension
CUI: C0085580
Disease: Essential Hypertension
0.030 GeneticVariation BEFREE Our results demonstrate a strong genetic heterogeneity among the ethnic group and suggest that the Gly40Ser mutation of the glucagon receptor gene plays little role, if any, in the pathogenesis of type 2 diabetes and essential hypertension in the Taiwanese population. 10090412 1999
Essential Hypertension
CUI: C0085580
Disease: Essential Hypertension
0.030 GeneticVariation BEFREE Glucagon receptor gene mutation (Gly40Ser) in human essential hypertension: the PEGASE study. 10406817 1999
Essential Hypertension
CUI: C0085580
Disease: Essential Hypertension
0.030 GeneticVariation BEFREE 1.Previous glucagon receptor gene (GCGR) studies have shown a Gly40Ser mutation to be more prevalent in essential hypertension and to affect glucagon binding affinity to its receptor. 9673441 1998