Crohn Disease
|
|
0.850 |
GeneticVariation
|
GWASDB |
Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.
|
18587394 |
2008 |
Diabetes Mellitus, Insulin-Dependent
|
|
0.830 |
GeneticVariation
|
GWASDB |
Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.
|
19430480 |
2009 |
Diabetes Mellitus, Insulin-Dependent
|
|
0.830 |
GeneticVariation
|
GWASCAT |
Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.
|
19430480 |
2009 |
Crohn Disease
|
|
0.850 |
GeneticVariation
|
GWASCAT |
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.
|
21102463 |
2010 |
Crohn Disease
|
|
0.850 |
GeneticVariation
|
GWASDB |
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.
|
21102463 |
2010 |
Crohn Disease
|
|
0.850 |
GeneticVariation
|
BEFREE |
Allelic association analysis (two-tailed) showed that three of the five targeted SNPs were significantly associated with overall susceptibility for CD (ZNF365, r10995271, P = 0.001; PTPN2, rs1893217, P = 0.005; STAT3, rs744166, P = 0.01).
|
20222910 |
2010 |
Celiac Disease
|
|
0.800 |
GeneticVariation
|
GWASDB |
Multiple common variants for celiac disease influencing immune gene expression.
|
20190752 |
2010 |
Celiac Disease
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Multiple common variants for celiac disease influencing immune gene expression.
|
20190752 |
2010 |
Crohn Disease
|
|
0.850 |
GeneticVariation
|
GWASDB |
A meta-analysis of genome-wide association scans identifies IL18RAP, PTPN2, TAGAP, and PUS10 as shared risk loci for Crohn's disease and celiac disease.
|
21298027 |
2011 |
Diabetes Mellitus, Insulin-Dependent
|
|
0.830 |
GeneticVariation
|
GWASDB |
A genome-wide meta-analysis of six type 1 diabetes cohorts identifies multiple associated loci.
|
21980299 |
2011 |
Autoimmune Diseases
|
|
0.810 |
GeneticVariation
|
GWASDB |
Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci.
|
21383967 |
2011 |
Autoimmune Diseases
|
|
0.810 |
GeneticVariation
|
GWASCAT |
Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci.
|
21383967 |
2011 |
Immune System Diseases
|
|
0.800 |
GeneticVariation
|
GWASDB |
Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci.
|
21383967 |
2011 |
Immune System Diseases
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci.
|
21383967 |
2011 |
Multiple Sclerosis
|
|
0.700 |
GeneticVariation
|
GWASDB |
Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci.
|
22190364 |
2011 |
Asthma
|
|
0.700 |
GeneticVariation
|
GWASDB |
Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia.
|
21150878 |
2011 |
Crohn Disease
|
|
0.850 |
GeneticVariation
|
BEFREE |
We identified a novel association between the genetic variant, rs1893217, located in intron 7 of the PTPN2 gene and CD.
|
22021207 |
2012 |
Inflammatory Bowel Diseases
|
|
0.810 |
GeneticVariation
|
GWASCAT |
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.
|
23128233 |
2012 |
Inflammatory Bowel Diseases
|
|
0.810 |
GeneticVariation
|
GWASDB |
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.
|
23128233 |
2012 |
Crohn Disease
|
|
0.850 |
GeneticVariation
|
BEFREE |
In stage 1, we observed associations between 5 intronic SNPs and CD including rs1893217 (P = 2 × 10⁻⁴), the SNP that is in perfect linkage disequilibrium with the lead genome-wide association studies SNP rs2542151.
|
23518806 |
2013 |
Diabetes Mellitus, Insulin-Dependent
|
|
0.830 |
GeneticVariation
|
BEFREE |
In children with the PTPN2 rs1893217 AA genotype, the VDR rs1544410 AA/AG genotype was associated with a decreased risk of T1D (HR: 0.24, 95% CI: 0.11-0.53, p=0.0004), while in children with the PTPN2 rs1893217 GG/GA genotype, the VDR rs1544410 AA/AG genotype was not associated with T1D (HR: 1.32, 95% CI: 0.43-4.06, p=0.62).
|
22960018 |
2013 |
Crohn Disease
|
|
0.850 |
GeneticVariation
|
BEFREE |
Moreover, a significant increase in CD risk for all carriers of the minor allele of rs1893217 (OR = 1.45, 95 % CI, 1.23-1.70, I (2) = 0 %) and rs7234029 (OR = 1.36, 95 % CI, 1.16-1.59, I (2) = 0 %) were found.
|
24127071 |
2014 |
Diabetes Mellitus, Insulin-Dependent
|
|
0.830 |
GeneticVariation
|
BEFREE |
The rs1893217 (T/C) polymorphism in PTPN2 gene is not associated with type 1 diabetes mellitus in subjects from Southern Brazil.
|
24936733 |
2014 |
Ulcerative Colitis
|
|
0.720 |
GeneticVariation
|
BEFREE |
The meta-analysis indicated that rs2542151, rs1893217 and rs1893217 were associated with increased CD risk, while the former was associated with increased UC risk.
|
24127071 |
2014 |
Behcet Syndrome
|
|
0.010 |
GeneticVariation
|
BEFREE |
PTPN2 variant rs1893217 was associated with risk of BD development in a Han Chinese population.
|
24480412 |
2014 |