rs2066702, ADH1B

N. diseases: 7
Disease: Alcoholic Intoxication, Chronic ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Alcoholic Intoxication, Chronic
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
0.720 GeneticVariation GWASCAT Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations. 30940813 2019
Alcoholic Intoxication, Chronic
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
0.720 GeneticVariation BEFREE In a genome-wide association study (GWAS), we identified highly significant associations between two population-specific functional variants in the alcohol dehydrogenase 1B gene (ADH1B) and AD in African-Americans (AAs; rs2066702) and European-Americans (EAs; rs1229984). 25828809 2016
Alcoholic Intoxication, Chronic
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
0.720 GeneticVariation GWASCAT Genome-wide association study of alcohol dependence:significant findings in African- and European-Americans including novel risk loci. 24166409 2014
Alcoholic Intoxication, Chronic
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
0.720 GeneticVariation BEFREE We tested the most significant ADH1B single nucleotide polymorphisms for alcohol dependence from a genomewide association study with this sample, ADH1B-rs1229984 (Arg48His) and ADH1B-rs2066702 (Arg370Cys), in EA and AA subsamples, respectively. 25410943 2014