rs2237895, KCNQ1

N. diseases: 10
Disease: Gestational Diabetes ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Gestational Diabetes
CUI: C0085207
Disease: Gestational Diabetes
0.030 GeneticVariation BEFREE These polymorphisms were in or near the following genes: TCF7L2 (rs7903146), MTNR1B (rs10830963), IGF2BP2 (rs4402960), KCNJ11 (rs5219), CDKAL1 (rs7754840), KCNQ1 (rs2237892 and rs2237895) and GCK (rs4607517); while no association was found for PPARG with GDM risk. 23029294 2012
Gestational Diabetes
CUI: C0085207
Disease: Gestational Diabetes
0.030 GeneticVariation BEFREE KCNQ1 polymorphisms of rs2237892 and rs2237895 were significantly associated with the risk of GDM (P = 0.003 and 0.005, respectively). 19850681 2010
Gestational Diabetes
CUI: C0085207
Disease: Gestational Diabetes
0.030 GeneticVariation BEFREE Furthermore, rs2237892 and rs2237895 were nominally associated with a decreased insulinogenic index at the time of GDM diagnosis (p = 0.025 and p = 0.037), whereas no association was observed with measures of insulin resistance. 20606385 2010