Disease Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Carcinoma of bladder
CUI: C0699885
Disease: Carcinoma of bladder
0.860 GeneticVariation BEFREE Based on the statistical evidence, we can draw a conclusion that the rs2294008 polymorphism of PSCA gene is likely to play a role in cancer carcinogenesis, especially in gastric cancer and bladder cancer. 26308216 2016
Carcinoma of bladder
CUI: C0699885
Disease: Carcinoma of bladder
0.860 GeneticVariation BEFREE Overall, seven of the 14 variants were significantly associated with bladder cancer risk (p = 9.763 × 10(-3) for rs9642880 at 8q24.21, p = 3.004 × 10(-3) for rs2294008 at 8q24.3, p = 0.012 for rs798766 at 4p16.3, p = 0.034 for rs1495741 at 8p22, p = 2.306 × 10(-4) for GSTM1, p = 8.507 × 10(-8) for rs17674580 at 18q12.3, p = 7.179 × 10(-4) for rs10936599 at 3q26.2) and the odds ratios (ORs) ranged from 1.13 to 1.65. 24740636 2014
Carcinoma of bladder
CUI: C0699885
Disease: Carcinoma of bladder
0.860 GeneticVariation BEFREE The study suggests that anti-PSCA immunotherapy might be beneficial for bladder cancer patients with high tumor PSCA expression, which is statistically significantly associated with the presence of CT and TT genotypes of a common genetic variant, rs2294008. 23266392 2013
Carcinoma of bladder
CUI: C0699885
Disease: Carcinoma of bladder
0.860 GeneticVariation BEFREE In conclusion, a joint effect of two PSCA SNPs, rs2294008 and rs2978974, suggests that both variants may be important for bladder cancer susceptibility, possibly through different mechanisms that influence the control of mRNA expression and interaction with regulatory factors. 22416122 2012
Carcinoma of bladder
CUI: C0699885
Disease: Carcinoma of bladder
0.860 GeneticVariation BEFREE These results indicated that the rs2294008 polymorphism of PSCA gene may play a role in bladder cancer carcinogenesis and it could be served as a biomarker for genetic susceptibility to bladder cancer in Chinese populations. 20083643 2010
Carcinoma of bladder
CUI: C0699885
Disease: Carcinoma of bladder
0.860 GeneticVariation GWASDB A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci. 20972438 2010
Carcinoma of bladder
CUI: C0699885
Disease: Carcinoma of bladder
0.860 GeneticVariation GWASCAT A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci. 20972438 2010
Carcinoma of bladder
CUI: C0699885
Disease: Carcinoma of bladder
0.860 GeneticVariation GWASCAT Genetic variation in the prostate stem cell antigen gene PSCA confers susceptibility to urinary bladder cancer. 19648920 2009
Carcinoma of bladder
CUI: C0699885
Disease: Carcinoma of bladder
0.860 GeneticVariation GWASDB Genetic variation in the prostate stem cell antigen gene PSCA confers susceptibility to urinary bladder cancer. 19648920 2009
Carcinoma of bladder
CUI: C0699885
Disease: Carcinoma of bladder
0.860 GeneticVariation BEFREE Our data identify rs2294008 as a new bladder cancer susceptibility locus. 19648920 2009