rs237025, SUMO4;TAB2
N. diseases: 26
Source: ALL
Disease | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
Diabetes Mellitus, Non-Insulin-Dependent
|
0.100 | GeneticVariation | BEFREE | Many studies suggest that the <i>small ubiquitin-like modifier 4 (SUMO4)</i> M55V gene polymorphism (rs237025) may be associated with an increased risk of type 2 diabetes mellitus (T2DM). | 29163370 | 2017 | |||||
Diabetes Mellitus, Non-Insulin-Dependent
|
0.100 | GeneticVariation | BEFREE | The meta-analysis demonstrated that the G allele of the SUMO4 M55V polymorphism could be a susceptible risk locus to T2DM, mainly in the Chinese population, while the association in other ethnic population needs to be further validated in studies with relatively large samples. | 28494838 | 2017 | |||||
Diabetes Mellitus, Non-Insulin-Dependent
|
0.100 | GeneticVariation | BEFREE | The small ubiquitin-like modifier 4 (SUMO4) rs237025 polymorphism has been reported to be associated with type 2 diabetes mellitus (T2DM). | 28689037 | 2017 | |||||
Diabetes Mellitus, Non-Insulin-Dependent
|
0.100 | GeneticVariation | BEFREE | SUMO4 163 G>A variation is associated with kidney disease in Indian subjects with type 2 diabetes. | 27055882 | 2016 | |||||
Diabetes Mellitus, Non-Insulin-Dependent
|
0.100 | GeneticVariation | BEFREE | It was found that SUMO4 M55V polymorphism and type-2 diabetes were significantly associated with a possible SUMO4 region to type-2 diabetes susceptibility. | 25189908 | 2015 | |||||
Diabetes Mellitus, Non-Insulin-Dependent
|
0.100 | GeneticVariation | BEFREE | Our study demonstrates significant associations of SUMO4 M55V polymorphism with T1DM in Asian and Caucasian population and with T2DM in Asian population. | 22936652 | 2012 | |||||
Diabetes Mellitus, Non-Insulin-Dependent
|
0.100 | GeneticVariation | BEFREE | The study indicates that the SUMO4 gene M55V variant was not associated with the susceptibility of the type 2 diabetes polymorphism. | 20728233 | 2010 | |||||
Diabetes Mellitus, Non-Insulin-Dependent
|
0.100 | GeneticVariation | BEFREE | This study suggests that in Taiwan the SUMO4 Met 55Val polymorphism is associated with susceptibility to T2DM and Type 2 diabetic patients with GG genotype have worse glycemic control. | 19915388 | 2010 | |||||
Diabetes Mellitus, Non-Insulin-Dependent
|
0.100 | GeneticVariation | BEFREE | SUMO4 Met55Val polymorphism is associated with coronary heart disease in Japanese type 2 diabetes individuals. | 19410319 | 2009 | |||||
Diabetes Mellitus, Non-Insulin-Dependent
|
0.100 | GeneticVariation | BEFREE | CONCLUSIONS-This study indicates that the SUMO4 gene M55V variant is associated with severity of diabetic nephropathy in patients with type 2 diabetes. | 17229939 | 2007 | |||||
Diabetes Mellitus, Non-Insulin-Dependent
|
0.100 | GeneticVariation | BEFREE | These data, together with previous reports, suggest the contribution of the SUMO4 Met55Val polymorphism to both type 1 and type 2 diabetes susceptibility in the Japanese population. | 17374705 | 2007 |