rs25487, XRCC1

N. diseases: 205
Disease: Ulcerative Colitis ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Ulcerative Colitis
CUI: C0009324
Disease: Ulcerative Colitis
0.020 GeneticVariation BEFREE Polymorphisms in XRCC1 Arg399Gln and APE1 Asp148Glu significantly increased the rate of apoptosis and risk of ulcerative colitis. 22193858 2012
Ulcerative Colitis
CUI: C0009324
Disease: Ulcerative Colitis
0.020 GeneticVariation BEFREE XRCC1 Arg399Gln and GSTP1 Ile104Val polymorphisms may influence the CIHM status in the rectal mucosa of UC patients and may be substantially involved in UC-associated carcinogenesis. 21234761 2011