|
Parkinson Disease
|
|
0.860 |
GeneticVariation
|
BEFREE |
After narrowing down the variants using the <i>p</i> < 1 × 10<sup>-5</sup> cutoff, in overall populations, seven SNPs increased the risk of PD (rs2736990, rs356220, rs356165, rs181489, rs356219, rs11931074, and rs2737029, with odds ratios [ORs] of 1.22-1.38) and one SNP decreased the risk (rs356186, with an OR of 0.77).
|
30410434 |
2018 |
|
Parkinson Disease
|
|
0.860 |
GeneticVariation
|
BEFREE |
Our meta-analysis provides evidence that the T allele, TT and TC genotype of rs2736990(C/T) polymorphism may decrease the risk of PD.
|
28844730 |
2017 |
|
Parkinson Disease
|
|
0.860 |
GeneticVariation
|
GWASDB |
Identification of a novel Parkinson's disease locus via stratified genome-wide association study.
|
24511991 |
2014 |
|
Parkinson Disease
|
|
0.860 |
GeneticVariation
|
BEFREE |
Our study demonstrated that SNCA rs2736990 C > T polymorphism was associated with susceptibility to PD in Chinese Han population.
|
24005725 |
2014 |
|
Parkinson Disease
|
|
0.860 |
GeneticVariation
|
BEFREE |
Our results show that rs2736990 and rs356220 in SNCA decreased the risk for PD in a Chinese population.
|
25129240 |
2014 |
|
Parkinson Disease
|
|
0.860 |
GeneticVariation
|
GWASDB |
Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database.
|
22438815 |
2012 |
|
Parkinson Disease
|
|
0.860 |
GeneticVariation
|
BEFREE |
In the additive model, SNP rs2736990 was significantly related to the risk of sporadic PD: the adjusted OR was 1.30 (95% CI: 1.002-1.68).
|
22425546 |
2012 |
|
Parkinson Disease
|
|
0.860 |
GeneticVariation
|
GWASDB |
Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease.
|
21738487 |
2011 |
|
Parkinson Disease
|
|
0.860 |
GeneticVariation
|
BEFREE |
Direct replication of SNPs within SNCA and BST1 confirmed these two genes to be associated with PD in the Netherlands (SNCA, rs2736990: P = 1.63 × 10(-5), OR = 1.325 and BST1, rs12502586: P = 1.63 × 10(-3), OR = 1.337).
|
21248740 |
2011 |
|
Parkinson Disease
|
|
0.860 |
GeneticVariation
|
GWASCAT |
Genome-wide association study confirms SNPs in SNCA and the MAPT region as common risk factors for Parkinson disease.
|
20070850 |
2010 |
|
Parkinson Disease
|
|
0.860 |
GeneticVariation
|
GWASDB |
Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson's disease.
|
20711177 |
2010 |
|
Parkinson Disease
|
|
0.860 |
GeneticVariation
|
GWASDB |
Genome-wide association study confirms SNPs in SNCA and the MAPT region as common risk factors for Parkinson disease.
|
20070850 |
2010 |
|
Parkinson Disease
|
|
0.860 |
GeneticVariation
|
GWASDB |
Genome-wide association study reveals genetic risk underlying Parkinson's disease.
|
19915575 |
2009 |
|
Parkinson Disease
|
|
0.860 |
GeneticVariation
|
GWASCAT |
Genome-wide association study reveals genetic risk underlying Parkinson's disease.
|
19915575 |
2009 |