rs28934578, TP53

N. diseases: 47
Disease: Lymphoma ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Lymphoma
CUI: C0024299
Disease: Lymphoma
0.010 GeneticVariation BEFREE We previously showed that the HSP90 inhibitor ganetespib potently suppresses T-lymphoma initiation and progression and extends overall survival (OS) in hotspot knockin mice expressing the p53 gain-of-function mutants R175H and R248Q (mutp53) by 30-59%. 28300840 2017