rs28934578, TP53

N. diseases: 47
Disease: Squamous cell carcinoma of pharynx ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Squamous cell carcinoma of pharynx
CUI: C1319317
Disease: Squamous cell carcinoma of pharynx
0.010 GeneticVariation BEFREE Using short hairpin RNA against p53, transient ectopic expression of wild-type p53 or mutant p53 (R248W or R175H), and a p53- and p21-dependent luciferase reporter assay, we demonstrated that growth arrest and apoptosis of FaDu (human pharyngeal squamous cell carcinoma), Hep3B (hepatoma), and MG-63 (osteosarcoma) cells induced by aloe-emodin (AE) are p53-independent. 21308745 2011