Disease: Glaucoma ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Glaucoma
CUI: C0017601
Disease: Glaucoma
0.030 GeneticVariation BEFREE The protein-coding SIX6 variant rs33912345, previously associated with POAG, has a functional effect on glaucoma-associated optic nerve head traits in Europeans. 30005032 2018
Glaucoma
CUI: C0017601
Disease: Glaucoma
0.030 GeneticVariation BEFREE Significant genetic association was identified for rs10483727 in HTG (P=0.02; odds ratio (OR)=1.31), NTG (P=7.41×10(-6); OR=2.71), and POAG (i.e., HTG and NTG combined; P=0.001; OR=1.44). rs33912345 was also significantly associated with HTG (P=0.008; OR=1.36), NTG(P=2.72×10(-6); OR=2.27), and POAG (P=3.84×10(-4); OR=1.49). 27260188 2016
Glaucoma
CUI: C0017601
Disease: Glaucoma
0.030 GeneticVariation BEFREE Recently the common SIX6 missense variant rs33912345 was found to be highly associated with glaucoma. 25537207 2014