rs35801418, LRRK2

N. diseases: 7
Disease: Parkinson Disease ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Parkinson Disease
CUI: C0030567
Disease: Parkinson Disease
0.030 GeneticVariation BEFREE The PD-causative Y1699C mutation mapped to the COR domain was previously reported to reduce the GTPase activity of full-length LRRK2. 30091236 2018
Parkinson Disease
CUI: C0030567
Disease: Parkinson Disease
0.030 GeneticVariation BEFREE This is the first report describing an Asian PD family with the p.Tyr1699Cys mutation in LRRK2. 22162019 2012
Parkinson Disease
CUI: C0030567
Disease: Parkinson Disease
0.030 GeneticVariation BEFREE The Y1699C mutation was absent from this PD sample. 20727385 2010