rs397507444, MTHFR

N. diseases: 306
Disease: 5,10-Methylenetetrahydrofolate reductase deficiency ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
5,10-Methylenetetrahydrofolate reductase deficiency
CUI: C0268615
Disease: 5,10-Methylenetetrahydrofolate reductase deficiency
0.010 GeneticVariation BEFREE We designed 4 amplicons bracketing the F5 [coagulation factor V (proaccelerin, labile factor)] 1691G>A, MTHFR (NADPH) 1298A>C, MTHFR 677C>T, and F2 [coagulation factor II (thrombin)] 20210G>A gene variants to melt at different temperatures by varying amplicon length and adding GC- or AT-rich 5' tails to selected primers. 17981920 2008