rs4072037, MUC1

N. diseases: 22
Disease: Malignant Neoplasms ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Malignant Neoplasms
CUI: C0006826
Disease: Malignant Neoplasms
0.030 GeneticVariation BEFREE It showed the MUC1 rs4072037</span> polymorphism was associated with decreased cancer</span> risk in four genetic models (G <i>vs.</i> A: OR=0.79, 95%CI: 0.71-0.89, <i>P</i>< 0.001; AG <i>vs.</i> AA: OR=0.72, 95%CI: 0.62-0.82, <i>P</i>< 0.001; GG <i>vs.</i> AA: OR=0.78, 95%CI: 0.69-0.88, <i>P</i>< 0.001; AG+GG <i>vs.</i> AA: OR=0.72, 95%CI: 0.63-0.83, <i>P</i>< 0.001). 30271495 2018
Malignant Neoplasms
CUI: C0006826
Disease: Malignant Neoplasms
0.030 GeneticVariation BEFREE In contrast, MUC1 rs4072037 was shown to decrease the cancer risk (CT vs. TT: adjusted OR = 0.77, 95% CI = 0.60-0.98). 25658482 2015
Malignant Neoplasms
CUI: C0006826
Disease: Malignant Neoplasms
0.030 GeneticVariation BEFREE Overall, the MUC1 rs4072037 polymorphism was associated with risk of c</span>ancer in all genetic models (G vs A: OR = 0.71, 95%CI: 0.63-0.80, p<0.01; GA vs AA: OR = 0.61, 95%CI:0.55-0.67, p<0.01; GG vs AA: OR = 0.58, 95%CI: 0.47-0.71, p<0.01; AG+AA vs GG: OR = 0.60, 95%CI: 0.55-0.60, p<0.01; GG vs AG+AA: OR = 0.70, 95%CI: 0.58-0.85, p<0.01). 24755768 2014