rs4149584, TNFRSF1A

N. diseases: 24
Disease: Autoinflammatory disease ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Autoinflammatory disease
CUI: C3267073
Disease: Autoinflammatory disease
0.010 GeneticVariation BEFREE Patients with the autoinflammatory disease Tumour Necrosis Factor receptor-associated periodic syndrome (TRAPS) who suffer from demyelinating disease have been described, and one of the milder TRAPS mutations (R92Q in the TNFRSF1A gene) has been suggested as a risk factor for multiple sclerosis (MS). 21565411 2011