rs4774, CIITA

N. diseases: 7
Disease: Multiple Sclerosis ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Multiple Sclerosis
CUI: C0026769
Disease: Multiple Sclerosis
0.030 GeneticVariation BEFREE We also confirm interaction between rs4774 and HLA-DRB1*15:01 such that individuals carrying the risk allele for rs4774 and HLA-DRB1*15:01 have a higher than expected risk for MS. 24430172 2014
Multiple Sclerosis
CUI: C0026769
Disease: Multiple Sclerosis
0.030 GeneticVariation BEFREE Recently the rs4774 CIITA missense variant (+1632G/C) was reported to be associated with susceptibility to multiple sclerosis. 21614020 2011
Multiple Sclerosis
CUI: C0026769
Disease: Multiple Sclerosis
0.030 GeneticVariation BEFREE Rs4774 (missense +1614G/C; G500A) was associated with MS (P = 4.9 x 10(-3)), particularly in DRB1*1501 +individuals (P = 1 x 10(-4)). 20211854 2010
Multiple Sclerosis
CUI: C0026769
Disease: Multiple Sclerosis
0.030 GeneticVariation BEFREE Rs4774 (missense +1614G/C; G500A) was associated with MS (P = 4.9 x 10(-3)), particularly in DRB1*1501 +individuals (P = 1 x 10(-4)). 20211854 2010