|
Coronary Artery Disease
|
|
0.710 |
GeneticVariation
|
BEFREE |
The rs495828 CAD risk allele was associated with higher MEA platelet aggregation; arachidonic acid: 14.9% (6.7-23.7%, p = 0.0002) higher AUC (Area Under aggregation Curve) per risk allele, and collagen: 13.1% (5.8%-20.9%, p = 0.0003).
|
30837090 |
2019 |
|
Coughing
|
|
0.020 |
GeneticVariation
|
BEFREE |
We found that genetic polymorphisms in BDKRB2 [rs8016905; P=0.003; odds ratio (OR)=2.21] and ABO (rs495828; P=0.001; OR=2.45) are associated with ACEi-induced cough after correction for multiple testing.
|
21832968 |
2011 |
|
Coughing
|
|
0.020 |
GeneticVariation
|
BEFREE |
The rs495828 polymorphism was associated with enalapril-induced cough and may serve as a useful pharmacogenomics marker of the safety of enalapril in Chinese patients with essential hypertension.
|
24743543 |
2014 |
|
Primary malignant neoplasm
|
|
0.010 |
GeneticVariation
|
BEFREE |
The T alleles of rs495828 and rs657152 were also significantly associated with an elevated cancer risk (adjusted OR = 1.58, 95% CI: 1.17-2.14; adjusted OR = 1.51, 95% CI: 1.09-2.10).
|
23816557 |
2014 |
|
Paroxysmal nocturnal hemoglobinuria
|
|
0.010 |
GeneticVariation
|
BEFREE |
Multivariate regression analysis showed larger PNH clone and genotypes with rs495828/rs2519093 minor allele as independent risk factors for thrombosis in PNH.
|
29190926 |
2017 |
|
Malignant Neoplasms
|
|
0.010 |
GeneticVariation
|
BEFREE |
The T alleles of rs495828 and rs657152 were also significantly associated with an elevated cancer risk (adjusted OR = 1.58, 95% CI: 1.17-2.14; adjusted OR = 1.51, 95% CI: 1.09-2.10).
|
23816557 |
2014 |
|
Hypertensive disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
A total of 10 haplotype-tagging single-nucleotide polymorphisms in ACE, the ACE I/D polymorphism, and 2 polymorphisms in the ABO (rs495828 and rs8176746) were investigated for association with hypertension in 269 hypertensive patients and 254 healthy controls.
|
22258027 |
2012 |
|
Essential Hypertension
|
|
0.010 |
GeneticVariation
|
BEFREE |
The rs495828 polymorphism was associated with enalapril-induced cough and may serve as a useful pharmacogenomics marker of the safety of enalapril in Chinese patients with essential hypertension.
|
24743543 |
2014 |
|
Venous Thromboembolism
|
|
0.800 |
GeneticVariation
|
GWASCAT |
A genome-wide association study of venous thromboembolism identifies risk variants in chromosomes 1q24.2 and 9q.
|
22672568 |
2012 |
|
Coronary Artery Disease
|
|
0.710 |
GeneticVariation
|
GWASCAT |
Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.
|
29212778 |
2018 |
|
Hemoglobin measurement
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Genome-wide association study of hematological and biochemical traits in a Japanese population.
|
20139978 |
2010 |
|
Hematocrit procedure
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Genome-wide association study of hematological and biochemical traits in a Japanese population.
|
20139978 |
2010 |
|
Alkaline phosphatase measurement
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Genome-wide association study of hematological and biochemical traits in a Japanese population.
|
20139978 |
2010 |
|
Low density lipoprotein cholesterol measurement
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
|
30698716 |
2019 |
|
Alcohol consumption
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
|
30698716 |
2019 |
|
Eczema
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
|
30595370 |
2019 |
|
Blood Protein Measurement
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Genome and epigenome wide studies of neurological protein biomarkers in the Lothian Birth Cohort 1936.
|
31320639 |
2019 |
|
Hemoglobin measurement
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.
|
28017375 |
2017 |
|
Hematocrit procedure
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.
|
28017375 |
2017 |
|
Triglycerides measurement
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
|
30698716 |
2019 |
|
Red Blood Cell Count measurement
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Genome-wide association study of hematological and biochemical traits in a Japanese population.
|
20139978 |
2010 |
|
Red Blood Cell Count measurement
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.
|
28017375 |
2017 |
|
Venous Thromboembolism
|
|
0.800 |
GeneticVariation
|
GWASDB |
Genetics of venous thrombosis: insights from a new genome wide association study.
|
21980494 |
2011 |
|
Venous Thromboembolism
|
|
0.800 |
GeneticVariation
|
GWASDB |
A genome-wide association study of venous thromboembolism identifies risk variants in chromosomes 1q24.2 and 9q.
|
22672568 |
2012 |
|
von Willebrand's factor (lab test)
|
|
0.700 |
GeneticVariation
|
GWASDB |
Ischemic stroke is associated with the ABO locus: the EuroCLOT study.
|
23381943 |
2013 |