rs4986791, TLR4

N. diseases: 182
Disease: Guillain-Barre Syndrome ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Guillain-Barre Syndrome
CUI: C0018378
Disease: Guillain-Barre Syndrome
0.020 GeneticVariation BEFREE However, no associations were observed between the genotypes of the Asp299Gly and Thr399Ile SNPs and antecedent <i>C. jejuni</i> infection or disease severity in Bangladeshi patients with GBS. 31019995 2019
Guillain-Barre Syndrome
CUI: C0018378
Disease: Guillain-Barre Syndrome
0.020 GeneticVariation BEFREE TLR4 (Asp299Gly) polymorphism was significantly associated with GBS (p, 0.045; OR, 8.75; 95% CI, 1.05-72.88); only acute motor axonal neuropathy (AMAN) was associated with Gly299Gly homozygote (p, 0.027; OR, 12.40; 95% CI, 1.33-115.77) and Thr399Ile (p, 0.019; OR, 3.42; 95% CI, 1.22-9.54) heterozygote, and TLR4-399Ile allele (p, 0.045; OR, 2.63; 95% CI, 1.02-6.75) compared to controls. 19913922 2010