rs5743708, TLR2

N. diseases: 98
Disease: Eczema ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Eczema
CUI: C0013595
Disease: Eczema
0.060 GeneticVariation BEFREE Our meta-analysis revealed a novel finding that the heterogeneous "GA" genotype of the TLR2 rs5743708 and "AG" genotype of the TLR4 rs4986790 may be associated with increased susceptibility to atopic dermatitis in Caucasians. 30273064 2019
Eczema
CUI: C0013595
Disease: Eczema
0.060 GeneticVariation BEFREE The TLR2 (R753Q and A-16934T) single nucleotide polymorphisms are not associated with atopic dermatitis in a group of Turkish patients. 28443596 2017
Eczema
CUI: C0013595
Disease: Eczema
0.060 GeneticVariation BEFREE RESULTS The frequency of the R753Q was significantly higher in AD children (16.0 percent) compared with controls (6.0 percent, P =0.004; OR2.99, 95 percent CI 1.39-6.41; RR 1.46, 95 percent CI 1.14-1.69). 22032785 2011
Eczema
CUI: C0013595
Disease: Eczema
0.060 GeneticVariation BEFREE Dysregulation of CD36 upon TLR-2 stimulation in monocytes from patients with atopic dermatitis and the TLR2 R753Q polymorphism. 19849713 2010
Eczema
CUI: C0013595
Disease: Eczema
0.060 GeneticVariation BEFREE Dysregulation of toll-like receptor-2 (TLR-2)-induced effects in monocytes from patients with atopic dermatitis: impact of the TLR-2 R753Q polymorphism. 18445187 2008
Eczema
CUI: C0013595
Disease: Eczema
0.060 GeneticVariation BEFREE Collectively, the outcome of innate and adaptive immune responses in AD is modulated by the TLR-2 R753Q SNP. 18234309 2008