rs5743708, TLR2

N. diseases: 98
Disease: Lyme Disease ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Lyme Disease
CUI: C0024198
Disease: Lyme Disease
0.020 GeneticVariation BEFREE The aim of the present study was to investigate the Arg753Gln single-nucleotide polymorphism (SNP) of the TLR2 gene, and the isoleucine to serine transversion at position 602 (Ile602Ser) of the TLR1 gene (previously associated with Lyme disease), in leptospirosis patients compared to healthy controls, carrying out a retrospective case/control study. 25784560 2015
Lyme Disease
CUI: C0024198
Disease: Lyme Disease
0.020 GeneticVariation BEFREE These data suggest that Arg753Gln may protect from the development of late stage LD due to a reduced signaling via TLR-2/TLR-1. 16081826 2005