rs5743708, TLR2

N. diseases: 98
Disease: Sepsis ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Sepsis
CUI: C0243026
Disease: Sepsis
0.030 GeneticVariation BEFREE The TLR2 Arg753Gln polymorphism might be used as a relevant risk estimate for the development of sepsis. 26616674 2015
Sepsis
CUI: C0243026
Disease: Sepsis
0.030 GeneticVariation BEFREE We investigated the supposed-2029C>T and 2258G>A TLR2 polymorphisms in 422 critically ill patients of European origin from southern Brazil (295 with sepsis and 127 without sepsis) and reviewed 33 studies on these polymorphisms, conducting a quality assessment with a score system. 20578945 2010
Sepsis
CUI: C0243026
Disease: Sepsis
0.030 GeneticVariation BEFREE Single nucleotide polymorphisms (SNPs) Arg753Gln and Arg677Trp affect TLR2 responsiveness and may contribute to the course of sepsis, which is associated with substantial morbidity and mortality during intensive care treatment. 18249133 2008