rs6265, BDNF;BDNF-AS

N. diseases: 272
Disease: Primary dysmenorrhea ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Primary dysmenorrhea
CUI: C0149875
Disease: Primary dysmenorrhea
0.030 GeneticVariation BEFREE We genotyped <i>BDNF</i> Val66Met SNP in 80 PDM females (20 Val/Val, 31 Val/Met, 29 Met/Met) and 76 healthy female controls (25 Val/Val, 36 Val/Met, 15 Met/Met). 30524221 2018
Primary dysmenorrhea
CUI: C0149875
Disease: Primary dysmenorrhea
0.030 GeneticVariation BEFREE Given that the brain derived neurotrophic factor (BDNF) acts as a pain modulator within the PAG and the BDNF Val66Met polymorphism contributes towards susceptibility to PDM, the present study of imaging genetics set out to investigate the influence of, firstly, the BDNF Val66Met single nucleotide polymorphism and, secondly, the genotype-pain interplays on the descending pain modulatory systems in the context of PAG-seeded FC patterning. 27010666 2016
Primary dysmenorrhea
CUI: C0149875
Disease: Primary dysmenorrhea
0.030 GeneticVariation BEFREE Our data also suggest the BDNF Val66Met polymorphism as a possible regulator of menstrual pain and pain-related emotions in PDM. 25383981 2014