|
Coronary heart disease
|
|
0.900 |
GeneticVariation
|
BEFREE |
Aldehyde dehydrogenase 2 (ALDH2) rs671 polymorphism is an established genetic risk of hypertension, diabetes, and coronary heart diseases in Asian population.
|
30846829 |
2020 |
|
Coronary heart disease
|
|
0.900 |
GeneticVariation
|
BEFREE |
Six common variants at ALDH2 gene, including rs2339840, rs4648328, rs4767939, rs11066028, rs16941669, and rs671, were selected to test the associations of those polymorphisms with the cardiovascular outcome in patients with CHD after PCI.
|
29742731 |
2018 |
|
Coronary heart disease
|
|
0.900 |
GeneticVariation
|
BEFREE |
Interactions between ALDH2 rs671 polymorphism and lifestyle behaviors on coronary artery disease risk in a Chinese Han population with dyslipidemia: A guide to targeted heart health management.
|
29960587 |
2018 |
|
Coronary heart disease
|
|
0.900 |
GeneticVariation
|
BEFREE |
Previous studies demonstrated that aldehyde dehydrogenase 2 (ALDH2) rs671 polymorphism, which eliminates ALDH2 activity down to 1%-6%, is a susceptibility gene for coronary disease.
|
27191745 |
2016 |
|
Coronary heart disease
|
|
0.900 |
GeneticVariation
|
BEFREE |
We genotyped rs671 of ALDH2 in 96 coronary heart disease (CHD) patients with four methods including high resolution melting analysis (HRM), TaqMan allelic discrimination assay (TaqMan), allele-specific PCR (AS-PCR) and pyrosequencing.
|
25803854 |
2015 |
|
Coronary heart disease
|
|
0.900 |
GeneticVariation
|
BEFREE |
The association between the aldehyde dehydrogenase 2 (ALDH2, rs671) genotypes and the estimated glomerular filtration rate (eGFR) was investigated in Japanese hypertensive patients with/without coronary artery disease or with ischemic heart failure (HF), and age/sex-matched normotensive healthy controls.
|
24067347 |
2014 |
|
Coronary heart disease
|
|
0.900 |
GeneticVariation
|
BEFREE |
ALDH2 Glu504Lys polymorphism and susceptibility to coronary artery disease and myocardial infarction in East Asians: a meta-analysis.
|
24333098 |
2014 |
|
Coronary heart disease
|
|
0.900 |
GeneticVariation
|
BEFREE |
The Glu504Lys polymorphism of aldehyde dehydrogenase 2 contributes to development of coronary artery disease.
|
25263942 |
2014 |
|
Coronary heart disease
|
|
0.900 |
GeneticVariation
|
BEFREE |
Our meta-analysis results showed that the A variant of the ALDH2 rs671 polymorphism may be associated with increase risks of CHD (odds ratios [OR]=1.36, 95% confidence interval [CI]=1.06-1.75, p=0.017) and MI (OR=1.64, 95% CI=1.22-2.20, p=0.001).
|
23697560 |
2013 |
|
Coronary heart disease
|
|
0.900 |
GeneticVariation
|
GWASCAT |
Genome-wide association study of coronary artery disease in the Japanese.
|
21971053 |
2012 |
|
Coronary heart disease
|
|
0.900 |
GeneticVariation
|
GWASDB |
Genome-wide association study of coronary artery disease in the Japanese.
|
21971053 |
2012 |
|
Coronary heart disease
|
|
0.900 |
GeneticVariation
|
BEFREE |
The ALDH2 Glu504Lys polymorphism is associated with coronary artery disease in Han Chinese: Relation with endothelial ADMA levels.
|
20417517 |
2010 |