rs6859, NECTIN2

N. diseases: 10
Disease: Coronary Arteriosclerosis ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Coronary Arteriosclerosis
CUI: C0010054
Disease: Coronary Arteriosclerosis
0.010 GeneticVariation BEFREE The high confidence (determined by miCLIP experiment) m<sup>6</sup>A-SNP rs6859 at the 3'-untranslated region of PVRL2 was associated with high-density lipoprotein cholesterol (P = 1.21 × 10<sup>-15</sup>), low-density lipoprotein cholesterol (P = 1.77 × 10<sup>-106</sup>), total cholesterol (P = 4.82 × 10<sup>-82</sup>), and triglycerides (P = 8.10 × 10<sup>-5</sup>) levels, coronary artery disease (P = 0.01), as well as PVRL2 mRNA expression in artery tibial (P = 2.38 × 10<sup>-6</sup>) and whole blood (P = 5.59 × 10<sup>-19</sup>). 30262821 2019