|
Myocardial Infarction
|
|
0.780 |
GeneticVariation
|
BEFREE |
We have previously shown that the C→T polymorphism (rs6929846) of the butyrophilin, subfamily 2, member A1 gene (BTN2A1) was significantly associated with myocardial infarction.
|
24452779 |
2014 |
|
Myocardial Infarction
|
|
0.780 |
GeneticVariation
|
BEFREE |
Multivariable logistic regression analyses with adjustment for covariates revealed that rs6929846 of BTN2A1 was significantly associated with MI in individuals with (P=0.0001; odds ratio, 1.49) or without (P=1.6x10-7; odds ratio, 2.32) hypertension; in individuals with (P=0.0002; odds ratio, 1.65) or without (P=8.1x10-7; odds ratio, 1.76) DM; and in individuals without CKD (P=6.0x10-11; odds ratio, 2.03), but not in those with CKD.
|
21347509 |
2011 |
|
Myocardial Infarction
|
|
0.780 |
GeneticVariation
|
BEFREE |
Given that diabetes mellitus is an important risk factor for myocardial infarction, the association of rs6929846 of BTN2A1 with myocardial infarction might be attributable, at least in part, to its effect on susceptibility to diabetes.
|
21672009 |
2011 |
|
Myocardial Infarction
|
|
0.780 |
GeneticVariation
|
BEFREE |
Given that metabolic syndrome (MetS) is an important risk factor for myocardial infarction, the association of the rs6929846 of BTN2A1 with myocardial infarction</span> might be attributable, at least in part, to its effect on susceptibility to MetS.
|
21784758 |
2011 |
|
Myocardial Infarction
|
|
0.780 |
GeneticVariation
|
BEFREE |
We showed that the C→T polymorphism (rs6929846) of BTN2A1 and A→G polymorphism (rs2569512) of ILF3 were significantly associated with myocardial infarction in Japanese individuals by a genome-wide association study.
|
21557786 |
2011 |
|
Myocardial Infarction
|
|
0.780 |
GeneticVariation
|
BEFREE |
Given that hypertension is a major risk factor for myocar</span>dial infarction, the association of rs6929846 of BTN2A1 with myocardial infarction</span> might be attributable, at least in part, to its effect on susceptibility to hypertension.
|
21525964 |
2011 |
|
Myocardial Infarction
|
|
0.780 |
GeneticVariation
|
BEFREE |
The results suggest that the relationship between rs6929846 of BTN2A1 or rs2569512 of ILF3 and MI is influenced by the serum concentrations of HDL and LDL cholesterol, respectively.
|
21468600 |
2011 |
|
Myocardial Infarction
|
|
0.780 |
GeneticVariation
|
BEFREE |
Seventy single nucleotide polymorphisms (SNPs) significantly (P<1.0×10(-7)) associated with MI by the GWAS were examined further in Japanese subject panel B, revealing two SNPs (rs6929846 of BTN2A1, rs2569512 of ILF3) to be significantly (P<0.0007) associated with MI.
|
21211798 |
2011 |
|
Myocardial Infarction
|
|
0.780 |
GeneticVariation
|
GWASDB |
The rs6929846 SNP of BTN2A1, but not rs2569512 of ILF3, was also significantly associated with MI in Japanese subject panel C. However, the association of neither rs6929846 nor rs2569512 with MI was replicated in the Korean population.
|
21211798 |
2011 |