|
Adrenocortical carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
The germline mutation, R342X (16915C>T), and the novel mutation, R342P (16916G>C), were found in a child with adrenocortical carcinoma and in a LFS pediatric patient with multiple primaries.
|
19714490 |
2009 |
|
Li-Fraumeni Syndrome
|
|
0.700 |
CausalMutation
|
CLINVAR |
De novo germline TP53 mutation presenting with synchronous malignancies of the central nervous system.
|
19711436 |
2009 |
|
Li-Fraumeni Syndrome
|
|
0.700 |
CausalMutation
|
CLINVAR |
Increased sperm aneuploidy in two male carriers of germline TP53 mutations.
|
21665182 |
2011 |
|
Li-Fraumeni Syndrome
|
|
0.700 |
CausalMutation
|
CLINVAR |
TP53 Mutational Status and Prediction of Benefit from Adjuvant 5-Fluorouracil in Stage III Colon Cancer Patients.
|
26425688 |
2015 |
|
Li-Fraumeni Syndrome
|
|
0.700 |
CausalMutation
|
CLINVAR |
Anaplastic rhabdomyosarcoma in TP53 germline mutation carriers.
|
24382691 |
2014 |
|
Li-Fraumeni Syndrome
|
|
0.700 |
CausalMutation
|
CLINVAR |
Oligomerization of p53 precedes its association with dynein and nuclear accumulation.
|
16969106 |
2006 |
|
Li-Fraumeni Syndrome
|
|
0.700 |
CausalMutation
|
CLINVAR |
Early onset HER2-positive breast cancer is associated with germline TP53 mutations.
|
21761402 |
2012 |
|
Li-Fraumeni Syndrome
|
|
0.700 |
CausalMutation
|
CLINVAR |
The germline mutation, R342X (16915C>T), and the novel mutation, R342P (16916G>C), were found in a child with adrenocortical carcinoma and in a LFS pediatric patient with multiple primaries.
|
19714490 |
2009 |
|
Li-Fraumeni Syndrome
|
|
0.700 |
CausalMutation
|
CLINVAR |
Detection of high frequency of mutations in a breast and/or ovarian cancer cohort: implications of embracing a multi-gene panel in molecular diagnosis in India.
|
26911350 |
2016 |
|
Li-Fraumeni Syndrome
|
|
0.700 |
CausalMutation
|
CLINVAR |
Complex analysis of the p53 tumor suppressor in lung carcinoma.
|
26718964 |
2016 |
|
Li-Fraumeni Syndrome
|
|
0.700 |
CausalMutation
|
CLINVAR |
TP53 mutations in Korean patients with non-small cell lung cancer.
|
20436704 |
2010 |
|
Li-Fraumeni Syndrome
|
|
0.700 |
CausalMutation
|
CLINVAR |
Telomere length in peripheral blood cells of germline TP53 mutation carriers is shorter than that of normal individuals of corresponding age.
|
17567834 |
2007 |
|
Neoplastic Syndromes, Hereditary
|
|
0.700 |
CausalMutation
|
CLINVAR |
p53 Tetramerization domain mutations: germline R342X and R342P, and somatic R337G identified in pediatric patients with Li-Fraumeni syndrome and a child with adrenocortical carcinoma.
|
19714490 |
2009 |
|
Neoplastic Syndromes, Hereditary
|
|
0.700 |
CausalMutation
|
CLINVAR |
Early onset HER2-positive breast cancer is associated with germline TP53 mutations.
|
21761402 |
2012 |
|
Neoplastic Syndromes, Hereditary
|
|
0.700 |
CausalMutation
|
CLINVAR |
Increased sperm aneuploidy in two male carriers of germline TP53 mutations.
|
21665182 |
2011 |
|
Neoplastic Syndromes, Hereditary
|
|
0.700 |
CausalMutation
|
CLINVAR |
Telomere length in peripheral blood cells of germline TP53 mutation carriers is shorter than that of normal individuals of corresponding age.
|
17567834 |
2007 |
|
Neoplastic Syndromes, Hereditary
|
|
0.700 |
CausalMutation
|
CLINVAR |
TP53 Mutational Status and Prediction of Benefit from Adjuvant 5-Fluorouracil in Stage III Colon Cancer Patients.
|
26425688 |
2015 |
|
Neoplastic Syndromes, Hereditary
|
|
0.700 |
CausalMutation
|
CLINVAR |
Detection of high frequency of mutations in a breast and/or ovarian cancer cohort: implications of embracing a multi-gene panel in molecular diagnosis in India.
|
26911350 |
2016 |
|
Neoplastic Syndromes, Hereditary
|
|
0.700 |
CausalMutation
|
CLINVAR |
Anaplastic rhabdomyosarcoma in TP53 germline mutation carriers.
|
24382691 |
2014 |
|
ovarian neoplasm
|
|
0.700 |
CausalMutation
|
CLINVAR |
|
|
|