rs7650466, EPHA3

N. diseases: 7
Disease: Cleft lip or lips ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Cleft lip or lips
CUI: C4321245
Disease: Cleft lip or lips
0.010 GeneticVariation BEFREE The rs7650466 T allele was associated with the incidence of NSCL/P (OR, 0.211; 95% CI, 0.131-0.338; adjusted p = 4.881 × 10<sup>-10</sup>) and cleft lip with or without palate (CL/P) (OR, 0.176; 95% CI, 0.104-0.297; adjusted p = 3.617 × 10<sup>-10</sup>), as well as with protective and dominant effects in both conditions. 29932736 2018