rs80338797, RAF1

N. diseases: 7
Disease: Deformity of bone ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Deformity of bone
CUI: C0410719
Disease: Deformity of bone
0.010 GeneticVariation BEFREE Our findings indicated that miR-195 inhibited WT and L613V RAF-1 induced hyperactive osteoblast differentiation in MC3T3-E1 cells by targeting RAF-1. miR-195 might be a novel therapeutic agent for the treatment of L613V-induced bone deformity in Noonan syndrome. 29197556 2018