rs870142, STX18-AS1

N. diseases: 7
Disease: Atrial Septal Defects ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Atrial Septal Defects
CUI: C0018817
Disease: Atrial Septal Defects
0.020 GeneticVariation BEFREE The allele A of rs870142, the allele A of rs16835979 and the allele A of rs6824295 were significantly associated with an increased risk of ASD. 26283177 2016
Atrial Septal Defects
CUI: C0018817
Disease: Atrial Septal Defects
0.020 GeneticVariation BEFREE Our study found that individuals carrying the allele T of rs870142, the allele A of rs16835979, and the allele T of rs6824295 had a respective 50.1% (odds ratio (OR) = 1.501, 95% confidence interval (CI) = 1.122-2.009, PFDR-BH = 0.018), 48.5% (OR = 1.485, 95%CI = 1.109-1.987, PFDR-BH = 0.012), and 38.6% (OR = 1.386, 95%CI = 1.042-1.844, PFDR-BH = 0.025) increased risk to develop ASD than wild-type allele carriers in our study cohort. 25875170 2015