rs9340799, ESR1

N. diseases: 62
Disease: Major Depressive Disorder ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Major Depressive Disorder
CUI: C1269683
Disease: Major Depressive Disorder
0.020 GeneticVariation BEFREE It appears unlikely that the common ESR1 variants rs2234693 and rs9340799 are associated with moderate depressive symptoms in women; however, there is some evidence that indicates a significant association with more severe depressive symptoms, major depressive disorder and anxiety. 22901010 2012
Major Depressive Disorder
CUI: C1269683
Disease: Major Depressive Disorder
0.020 GeneticVariation BEFREE Women homozygous for the variant G allele of ESR1 rs9340799 had a 1.6-fold increased risk of MDD across their lifetime compared with women who were homozygous for the A allele (p=0.009). 22051074 2012