Source: RGD

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 92
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962 90
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962 82
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962 76
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962 22
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923 86
HMOX1 P09601 heme oxygenase 1 9.7E-03 0.381 0.923 69
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923 62
IL18 Q14116 interleukin 18 3.1E-02 0.365 0.923 40
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923 35
CASP8 Q14790 caspase 8 Enzyme 3.7E-06 0.404 0.923 31
CXCL1 P09341 C-X-C motif chemokine ligand 1 Signaling 0.12 0.449 0.923 30
PLAU P00749 plasminogen activator, urokinase Enzyme 2.3E-06 0.425 0.923 26
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923 22
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923 11
DMD P11532 dystrophin 1.00 0.423 0.923 8
CCL4 P13236 Q8NHW4 C-C motif chemokine ligand 4 Signaling 0.24 0.466 0.923 5
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885 60
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885 44
BAX Q07812 BCL2 associated X, apoptosis regulator Signaling 0.32 0.417 0.885 44
NQO1 P15559 NAD(P)H quinone dehydrogenase 1 1.2E-09 0.434 0.885 40
CCR5 P51681 C-C motif chemokine receptor 5 (gene/pseudogene) G-protein coupled receptor 4.3E-10 0.398 0.885 26
CX3CR1 P49238 C-X3-C motif chemokine receptor 1 G-protein coupled receptor 6.1E-02 0.457 0.885 26
NR3C1 P04150 nuclear receptor subfamily 3 group C member 1 Nuclear receptor 0.97 0.393 0.885 26