Source: ANIMAL_MODELS

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
SYT10 Q6XYQ8 synaptotagmin 10 6.2E-05 0.931 0.077 1
SCN2B O60939 sodium voltage-gated channel beta subunit 2 Ion channel 1.7E-03 0.678 0.192 2
SYT4 Q9H2B2 synaptotagmin 4 Transporter 0.44 0.861 0.192 1
GRIK5 Q16478 glutamate ionotropic receptor kainate type subunit 5 Ion channel 0.99 0.792 0.231 3
BEX3 Q00994 brain expressed X-linked 3 0.62 0.780 0.346 3
HCN2 Q9UL51 hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2 Ion channel 0.49 0.653 0.385 7
YWHAB P31946 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta Chaperone 0.98 0.769 0.385 2
NPY1R P25929 neuropeptide Y receptor Y1 G-protein coupled receptor 4.3E-02 0.628 0.423 12
C7 P10643 complement C7 1.1E-14 0.751 0.423 3
HRH3 Q9Y5N1 histamine receptor H3 G-protein coupled receptor 4.1E-02 0.647 0.462 12
NPY5R Q15761 neuropeptide Y receptor Y5 G-protein coupled receptor 6.4E-03 0.691 0.462 8
VDAC2 P45880 voltage dependent anion channel 2 0.63 0.674 0.462 3
MBD3 O95983 methyl-CpG binding domain protein 3 0.98 0.682 0.462 2
SLC6A11 P48066 solute carrier family 6 member 11 Transporter 4.8E-05 0.716 0.462 2
ENDOG Q14249 endonuclease G 1.8E-04 0.656 0.500 6
SLC38A3 Q99624 solute carrier family 38 member 3 Transporter 0.711 0.500 3
MAP1B P46821 microtubule associated protein 1B Cellular structure 1.00 0.628 0.500 2
KDM3B Q7LBC6 lysine demethylase 3B Epigenetic regulator 1.00 0.686 0.500 2
SH3GL2 Q99962 SH3 domain containing GRB2 like 2, endophilin A1 1.2E-04 0.659 0.500 1
ABAT P80404 4-aminobutyrate aminotransferase Enzyme 6.3E-03 0.628 0.538 16
NEURL1 O76050 neuralized E3 ubiquitin protein ligase 1 Enzyme 1.1E-02 0.556 0.538 1
GRIA1 P42261 glutamate ionotropic receptor AMPA type subunit 1 Ion channel 1.00 0.570 0.577 9
SREBF2 Q12772 sterol regulatory element binding transcription factor 2 0.21 0.566 0.577 9
KCNA1 Q09470 potassium voltage-gated channel subfamily A member 1 Ion channel 7.6E-02 0.573 0.577 8