Source: INFERRED

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923 283
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885 191
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923 341
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962 191
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885 59
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846 342
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923 382
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923 133
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923 67
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923 94
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885 153
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923 48
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885 135
NLRP3 Q96P20 NLR family pyrin domain containing 3 8.1E-04 0.361 0.962 112
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885 330
TP63 Q9H3D4 tumor protein p63 Transcription factor 1.00 0.362 0.769 266
KIT P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 0.98 0.366 0.808 94
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923 170
NOTCH1 P46531 notch receptor 1 1.00 0.369 0.885 85
TERT O14746 telomerase reverse transcriptase Enzyme 0.99 0.374 0.846 142
EZH2 Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit Epigenetic regulator 1.00 0.376 0.885 91
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885 229
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846 218
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808 381