Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
HLA-DRB1 P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1.1E-03 0.333 0.923 18 140
HLA-DPB1 P04440 major histocompatibility complex, class II, DP beta 1 Immune response 5.3E-10 0.453 0.923 8 97
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923 3 4
CD69 Q07108 CD69 molecule 3.0E-02 0.488 0.923 2 1
HLA-B P01889 major histocompatibility complex, class I, B 3.9E-05 0.379 0.885 30 202
IL2RA P01589 interleukin 2 receptor subunit alpha Receptor 5.5E-02 0.389 0.885 14 12
AGER Q15109 advanced glycosylation end-product specific receptor Receptor 6.4E-16 0.420 0.885 6 6
LTA P01374 lymphotoxin alpha Signaling 0.20 0.434 0.885 2 8
TH P07101 tyrosine hydroxylase 1.7E-06 0.462 0.885 1 3
HLA-DQA1 P01909 major histocompatibility complex, class II, DQ alpha 1 Immune response 2.4E-02 0.416 0.846 23 65
HLA-A P04439 major histocompatibility complex, class I, A 1.3E-03 0.370 0.846 22 36
POU5F1 Q01860 POU class 5 homeobox 1 0.95 0.441 0.846 15 14
PTPN22 Q9Y2R2 protein tyrosine phosphatase non-receptor type 22 3.5E-21 0.438 0.846 13 4
MICA Q29983 MHC class I polypeptide-related sequence A 5.0E-03 0.473 0.846 11 17
HLA-DPA1 P20036 major histocompatibility complex, class II, DP alpha 1 Immune response 2.5E-06 0.552 0.846 7 49
COL1A2 P08123 collagen type I alpha 2 chain 1.00 0.486 0.846 3 3
MEG3 maternally expressed 3 0.471 0.846 1 1
ATXN2 Q99700 ataxin 2 Nucleic acid binding 0.85 0.482 0.808 32 28
BTNL2 Q9UIR0 butyrophilin like 2 Enzyme modulator 8.6E-11 0.546 0.808 18 58
HCP5 Q6MZN7 HLA complex P5 0.595 0.808 14 16
TAP2 Q03519 transporter 2, ATP binding cassette subfamily B member Transporter 6.9E-11 0.517 0.808 12 19
DDX39B Q13838 DExD-box helicase 39B 1.00 0.641 0.808 12 19
EHMT2 Q96KQ7 euchromatic histone lysine methyltransferase 2 Epigenetic regulator 1.0E-04 0.590 0.808 7 7
ERBB3 P21860 erb-b2 receptor tyrosine kinase 3 Kinase 1.7E-15 0.448 0.808 6 4