Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
IL6 P05231 interleukin 6 0.32 0.248 0.962 2132 21
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 1604 22
IFNG P01579 interferon gamma 0.47 0.288 0.962 1361 10
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885 1156 29
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962 886 50
LEP P41159 leptin 0.46 0.349 0.846 807 13
MIR21 microRNA 21 0.363 0.846 705 2
MTCO2P12 MT-CO2 pseudogene 12 0.368 0.962 703 0
ADIPOQ Q15848 adiponectin, C1Q and collagen domain containing 4.6E-09 0.376 0.885 607 44
MIR155 microRNA 155 0.384 0.885 573 1
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923 572 22
EPO P01588 erythropoietin 1.1E-02 0.381 0.885 560 4
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885 559 37
POLDIP2 Q9Y2S7 DNA polymerase delta interacting protein 2 0.41 0.396 0.923 528 3
HMOX1 P09601 heme oxygenase 1 9.7E-03 0.381 0.923 510 6
MIR146A microRNA 146a 0.398 0.885 492 3
CCR2 P41597 C-C motif chemokine receptor 2 2.3E-02 0.418 0.846 410 6
CDKN1B P46527 cyclin dependent kinase inhibitor 1B 0.62 0.409 0.769 373 7
FOXO3 O43524 forkhead box O3 0.99 0.431 0.808 355 13
MIR223 microRNA 223 0.433 0.808 347 0
CLU P10909 clusterin 7.8E-05 0.426 0.885 343 12
MIR145 microRNA 145 0.431 0.846 343 4
PTCH1 Q13635 patched 1 1.00 0.398 0.885 339 25
TSPO P30536 translocator protein 2.7E-04 0.444 0.885 334 1