Source: GWASCAT

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923 9 3
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923 10 10
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962 9 3
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923 7 6
NOTCH1 P46531 notch receptor 1 1.00 0.369 0.885 9 4
HLA-B P01889 major histocompatibility complex, class I, B 3.9E-05 0.379 0.885 94 101
IL13 P35225 interleukin 13 1.4E-02 0.386 0.846 9 6
IL2RA P01589 interleukin 2 receptor subunit alpha Receptor 5.5E-02 0.389 0.885 39 22
NFKB1 P19838 nuclear factor kappa B subunit 1 Transcription factor 1.00 0.396 0.923 18 12
CD40 P25942 CD40 molecule 0.85 0.396 0.846 9 3
ESR2 Q92731 estrogen receptor 2 Nuclear receptor 4.5E-08 0.400 0.923 11 10
TNFRSF1A P19438 TNF receptor superfamily member 1A 0.99 0.409 0.923 13 6
AHR P35869 aryl hydrocarbon receptor Transcription factor 1.00 0.410 0.923 19 8
CASR P41180 calcium sensing receptor G-protein coupled receptor 4.7E-02 0.410 0.846 4 7
MGMT P16455 O-6-methylguanine-DNA methyltransferase 1.2E-07 0.412 0.885 7 5
SMAD3 P84022 SMAD family member 3 Transcription factor 0.80 0.415 0.923 53 31
NOD2 Q9HC29 nucleotide binding oligomerization domain containing 2 Enzyme 2.0E-30 0.423 0.923 9 8
RUNX1 Q01196 RUNX family transcription factor 1 Transcription factor 0.65 0.425 0.808 38 29
PLAU P00749 plasminogen activator, urokinase Enzyme 2.3E-06 0.425 0.923 7 3
STK11 Q15831 serine/threonine kinase 11 Kinase 0.99 0.435 0.808 5 1
PTPN22 Q9Y2R2 protein tyrosine phosphatase non-receptor type 22 3.5E-21 0.438 0.846 34 1
ETS1 P14921 ETS proto-oncogene 1, transcription factor Transcription factor 0.78 0.444 0.731 24 18
DNMT3A Q9Y6K1 DNA methyltransferase 3 alpha 7.4E-39 0.445 0.846 12 9
PRKCB P05771 protein kinase C beta Kinase 1.00 0.453 0.885 10 8