Source: ALL

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885 1368 68
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923 702 98
NOTCH1 P46531 notch receptor 1 1.00 0.369 0.885 693 64
KMT2A Q03164 lysine methyltransferase 2A 1.00 0.410 0.885 535 65
COL2A1 P02458 collagen type II alpha 1 chain 1.00 0.444 0.846 496 96
CREBBP Q92793 CREB binding protein 1.00 0.428 0.808 438 123
CHD7 Q9P2D1 chromodomain helicase DNA binding protein 7 1.00 0.441 0.846 419 247
ATRX P46100 ATRX chromatin remodeler 1.00 0.452 0.808 412 38
COL11A2 P13942 collagen type XI alpha 2 chain 0.70 0.435 0.846 399 37
GLI2 P10070 GLI family zinc finger 2 0.97 0.446 0.846 351 37
DNMT3A Q9Y6K1 DNA methyltransferase 3 alpha 7.4E-39 0.445 0.846 350 56
EP300 Q09472 E1A binding protein p300 1.00 0.459 0.846 345 48
KMT2D O14686 lysine methyltransferase 2D 1.00 0.465 0.808 320 266
FOXP1 Q9H334 forkhead box P1 1.00 0.460 0.808 317 64
BCOR Q6W2J9 BCL6 corepressor 1.00 0.471 0.808 314 21
ASXL1 Q8IXJ9 ASXL transcriptional regulator 1 1.3E-14 0.482 0.808 296 24
NHS Q6T4R5 NHS actin remodeling regulator 1.00 0.466 0.846 295 26
LRP5 O75197 LDL receptor related protein 5 0.51 0.485 0.846 283 99
COL1A2 P08123 collagen type I alpha 2 chain 1.00 0.486 0.846 271 178
ARID1B Q8NFD5 AT-rich interaction domain 1B 1.00 0.503 0.846 270 90
COL11A1 P12107 collagen type XI alpha 1 chain 1.00 0.495 0.846 268 41
SETBP1 Q9Y6X0 SET binding protein 1 1.00 0.503 0.808 257 28
SKI P12755 SKI proto-oncogene 1.00 0.503 0.808 255 22
SMC1A Q14683 structural maintenance of chromosomes 1A 1.00 0.509 0.808 251 53