Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
GCKR Q14397 glucokinase regulator 8.5E-19 0.604 0.615 37 18
HLA-B P01889 major histocompatibility complex, class I, B 3.9E-05 0.379 0.885 30 202
CYP21A2 P08686 cytochrome P450 family 21 subfamily A member 2 2.6E-04 0.525 0.769 27 62
FADS2 O95864 fatty acid desaturase 2 1.00 0.575 0.692 25 99
FADS1 O60427 fatty acid desaturase 1 0.37 0.582 0.769 22 20
FTO Q9C0B1 FTO alpha-ketoglutarate dependent dioxygenase 8.4E-08 0.486 0.885 19 64
LINC02571 long intergenic non-protein coding RNA 2571 0.743 0.500 18 42
TCF7L2 Q9NQB0 transcription factor 7 like 2 1.00 0.485 0.846 16 16
TMEM258 P61165 transmembrane protein 258 1.9E-03 0.644 0.654 14 28
ZPR1 O75312 ZPR1 zinc finger 8.9E-09 0.674 0.462 14 21
JMJD1C Q15652 jumonji domain containing 1C 1.00 0.517 0.769 13 20
CETP P11597 cholesteryl ester transfer protein 1.2E-23 0.512 0.731 12 69
APOB P04114 apolipoprotein B 1.9E-16 0.453 0.808 12 32
LDLR P01130 low density lipoprotein receptor 9.8E-24 0.449 0.885 12 22
UGT1A10 Q9HAW8 UDP glucuronosyltransferase family 1 member A10 4.6E-19 0.588 0.615 12 264
UGT1A8 Q9HAW9 UDP glucuronosyltransferase family 1 member A8 1.3E-09 0.588 0.654 12 284
NECTIN2 Q92692 nectin cell adhesion molecule 2 0.97 0.575 0.769 12 29
MYRF Q9Y2G1 myelin regulatory factor 1.00 0.584 0.731 12 32
LRP1 Q07954 LDL receptor related protein 1 1.00 0.482 0.769 11 11
UGT1A7 Q9HAW7 UDP glucuronosyltransferase family 1 member A7 8.7E-14 0.550 0.692 11 198
UGT1A6 P19224 UDP glucuronosyltransferase family 1 member A6 3.0E-07 0.560 0.654 11 157
UGT1A5 P35504 UDP glucuronosyltransferase family 1 member A5 9.4E-09 0.656 0.462 11 123
UGT1A9 O60656 UDP glucuronosyltransferase family 1 member A9 5.4E-08 0.590 0.577 11 227
UGT1A4 P22310 UDP glucuronosyltransferase family 1 member A4 6.0E-07 0.595 0.654 11 101