Source: GWASCAT

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962 9 11
MAPK14 Q16539 mitogen-activated protein kinase 14 Kinase 0.37 0.379 0.923 7 2
INS P01308 insulin 0.30 0.445 0.923 3 1
FTO Q9C0B1 FTO alpha-ketoglutarate dependent dioxygenase 8.4E-08 0.486 0.885 64 61
ABO P16442 ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase Enzyme 0.427 0.885 61 54
HLA-DQB1 P01920 major histocompatibility complex, class II, DQ beta 1 Immune response 8.9E-03 0.407 0.885 33 30
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885 26 10
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885 20 39
ANK1 P16157 ankyrin 1 1.00 0.540 0.885 9 14
NOX4 Q9NPH5 NADPH oxidase 4 Enzyme 5.8E-20 0.471 0.885 9 11
MASP1 P48740 mannan binding lectin serine peptidase 1 Enzyme 1.2E-11 0.565 0.885 6 3
TH P07101 tyrosine hydroxylase 1.7E-06 0.462 0.885 2 5
IGF2 P01344 insulin like growth factor 2 4.4E-02 0.390 0.885 1 8
TCF7L2 Q9NQB0 transcription factor 7 like 2 1.00 0.485 0.846 50 31
PTPN22 Q9Y2R2 protein tyrosine phosphatase non-receptor type 22 3.5E-21 0.438 0.846 34 1
AUTS2 Q8WXX7 activator of transcription and developmental regulator AUTS2 1.00 0.569 0.846 20 46
HNF1A P20823 HNF1 homeobox A Nucleic acid binding 0.96 0.478 0.846 20 21
ARG1 P05089 arginase 1 Enzyme 3.6E-04 0.476 0.846 14 10
POU5F1 Q01860 POU class 5 homeobox 1 0.95 0.441 0.846 14 11
ALK Q9UM73 ALK receptor tyrosine kinase Kinase 3.2E-06 0.396 0.846 13 6
UMOD P07911 uromodulin 3.1E-17 0.520 0.846 10 9
ABCC8 Q09428 ATP binding cassette subfamily C member 8 Transporter 8.0E-24 0.474 0.846 6 5
GLP1R P43220 glucagon like peptide 1 receptor G-protein coupled receptor 0.29 0.471 0.846 4 3
CASR P41180 calcium sensing receptor G-protein coupled receptor 4.7E-02 0.410 0.846 4 7