Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
JUP P14923 junction plakoglobin 8.0E-04 0.628 0.500 40
NIPAL4 Q0D2K0 NIPA like domain containing 4 1.4E-03 0.682 0.423 36
KDSR Q06136 3-ketodihydrosphingosine reductase 0.12 0.674 0.538 31
LIPN Q5VXI9 lipase family member N 3.1E-05 0.736 0.423 31
NLRP1 Q9C000 NLR family pyrin domain containing 1 5.0E-19 0.502 0.769 30
KRT1 P04264 keratin 1 0.74 0.575 0.654 28
CARD14 Q9BXL6 caspase recruitment domain family member 14 1.2E-19 0.546 0.846 22
CERS3 Q8IU89 ceramide synthase 3 5.7E-03 0.705 0.308 18
IL1RN P18510 interleukin 1 receptor antagonist 3.1E-02 0.373 0.923 15
CIB1 Q99828 calcium and integrin binding 1 3.3E-04 0.458 0.769 14
KRT10 P13645 keratin 10 2.5E-03 0.579 0.692 13
AAGAB Q6PD74 alpha and gamma adaptin binding protein 3.9E-07 0.695 0.538 12
POGLUT1 Q8NBL1 protein O-glucosyltransferase 1 1.6E-08 0.691 0.385 7
IL36RN Q9UBH0 interleukin 36 receptor antagonist 3.4E-08 0.638 0.538 6
CAST P20810 calpastatin 4.1E-12 0.541 0.846 6
EXPH5 Q8NEV8 exophilin 5 4.2E-26 0.792 0.154 4
KRT13 P13646 keratin 13 6.4E-04 0.631 0.692 3
KRT6C P48668 keratin 6C 3.8E-22 0.751 0.269 2
DSG1 Q02413 desmoglein 1 Cell adhesion 0.93 0.606 0.538 14
GJA1 P17302 gap junction protein alpha 1 Cell-cell junction 0.16 0.393 0.885 205
GJB3 O75712 gap junction protein beta 3 Cell-cell junction 2.2E-03 0.621 0.462 32
CLDN1 O95832 claudin 1 Cell-cell junction 1.0E-03 0.481 0.808 26
DSP P15924 desmoplakin Cellular structure 1.00 0.514 0.808 58
MBTPS2 O43462 membrane bound transcription factor peptidase, site 2 Enzyme 1.00 0.513 0.769 163