Source: ALL

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
IL6 P05231 interleukin 6 0.32 0.248 0.962 2367 22
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923 1679 21
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962 1483 15
SMUG1 Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 4.5E-04 0.322 0.923 1034 6
IL4 P05112 interleukin 4 4.7E-03 0.332 0.962 996 23
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885 985 137
LEP P41159 leptin 0.46 0.349 0.846 931 15
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923 774 33
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885 706 39
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962 703 681
CSF3 P09919 colony stimulating factor 3 0.38 0.377 0.885 687 4
HMOX1 P09601 heme oxygenase 1 9.7E-03 0.381 0.923 666 9
EPO P01588 erythropoietin 1.1E-02 0.381 0.885 646 11
IL13 P35225 interleukin 13 1.4E-02 0.386 0.846 587 9
CD14 P08571 CD14 molecule 4.9E-05 0.392 0.885 551 8
PTH P01270 parathyroid hormone 1.2E-02 0.397 0.846 528 10
PON1 P27169 paraoxonase 1 9.8E-11 0.409 0.885 496 29
TLR9 Q9NR96 toll like receptor 9 9.8E-06 0.411 0.885 457 11
CEACAM5 P06731 CEA cell adhesion molecule 5 4.2E-10 0.420 0.846 428 2
CHI3L1 P36222 chitinase 3 like 1 1.1E-05 0.419 0.885 420 9
HFE Q30201 homeostatic iron regulator 2.6E-08 0.436 0.846 415 59
IDH1 O75874 isocitrate dehydrogenase (NADP(+)) 1 2.6E-12 0.424 0.808 399 10
IDH2 P48735 isocitrate dehydrogenase (NADP(+)) 2 0.88 0.434 0.808 380 15
HAMP P81172 hepcidin antimicrobial peptide 8.2E-03 0.433 0.846 377 15