Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962 334
IL6 P05231 interleukin 6 0.32 0.248 0.962 262
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962 234
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 224
CAT P04040 catalase Enzyme 1.6E-10 0.359 0.962 169
IFNG P01579 interferon gamma 0.47 0.288 0.962 157
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962 148
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962 146
ALB P02768 albumin Transporter 0.64 0.317 0.962 122
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962 111
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962 76
IL1A P01583 interleukin 1 alpha 1.6E-04 0.333 0.962 68
IL4 P05112 interleukin 4 4.7E-03 0.332 0.962 62
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923 280
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923 160
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923 142
HMOX1 P09601 heme oxygenase 1 9.7E-03 0.381 0.923 135
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923 133
GSTP1 P09211 glutathione S-transferase pi 1 1.4E-02 0.383 0.923 98
AHR P35869 aryl hydrocarbon receptor Transcription factor 1.00 0.410 0.923 97
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923 96
HLA-DRB1 P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1.1E-03 0.333 0.923 58
GSTM1 P09488 glutathione S-transferase mu 1 2.1E-03 0.380 0.923 57
CYP1A2 P05177 cytochrome P450 family 1 subfamily A member 2 Enzyme 2.5E-10 0.494 0.923 50