Source: UNIPROT

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
MAP3K15 Q6ZN16 mitogen-activated protein kinase kinase kinase 15 2.9E-32 0.792 0.231 4 1
MYO18B Q8IUG5 myosin XVIIIB 1.0E-31 0.628 0.615 4 5
TRIM33 Q9UPN9 tripartite motif containing 33 1.00 0.626 0.577 2 0
KEAP1 Q14145 kelch like ECH associated protein 1 3.9E-04 0.475 0.808 2 0
CDKN2B P42772 cyclin dependent kinase inhibitor 2B 7.3E-03 0.417 0.769 1 1
CSNK1E P49674 casein kinase 1 epsilon 1.00 0.619 0.615 1 0
TAF1L Q8IZX4 TATA-box binding protein associated factor 1 like Epigenetic regulator 0.96 0.839 0.154 3 0
FGFR3 P22607 fibroblast growth factor receptor 3 Kinase 1.6E-05 0.391 0.846 17 14
TTN Q8WZ42 titin Kinase 2.6E-96 0.470 0.885 16 32
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808 13 34
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885 7 45
EPHA3 P29320 EPH receptor A3 Kinase 1.2E-05 0.497 0.692 6 3
ERN1 O75460 endoplasmic reticulum to nucleus signaling 1 Kinase 0.99 0.513 0.808 5 4
ATR Q13535 ATR serine/threonine kinase Kinase 3.5E-09 0.456 0.923 5 1
PRKDC P78527 protein kinase, DNA-activated, catalytic subunit Kinase 1.00 0.540 0.808 5 5
RAF1 P04049 Raf-1 proto-oncogene, serine/threonine kinase Kinase 0.85 0.418 0.885 5 17
TNK2 Q07912 tyrosine kinase non receptor 2 Kinase 8.2E-12 0.623 0.538 4 2
EPHA8 P29322 EPH receptor A8 Kinase 1.8E-10 0.686 0.346 4 0
GUCY2F P51841 guanylate cyclase 2F, retinal Kinase 1.1E-13 0.821 0.231 4 2
KDR P35968 kinase insert domain receptor Kinase 1.00 0.378 0.885 4 2
NEK1 Q96PY6 NIMA related kinase 1 Kinase 1.9E-25 0.575 0.769 4 2
NTRK2 Q16620 neurotrophic receptor tyrosine kinase 2 Kinase 1.00 0.479 0.808 4 4
NTRK3 Q16288 neurotrophic receptor tyrosine kinase 3 Kinase 1.00 0.522 0.692 4 2
TRPM6 Q9BX84 transient receptor potential cation channel subfamily M member 6 Kinase 2.7E-10 0.656 0.538 3 2