Source: HPO

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
MASP2 O00187 mannan binding lectin serine peptidase 2 Enzyme 3.0E-14 0.582 0.692 4
FMO3 P31513 flavin containing dimethylaniline monoxygenase 3 Enzyme 6.5E-16 0.638 0.500 8
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885 15
SMARCD2 Q92925 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 Nucleic acid binding 6.5E-05 0.700 0.385 16
MTHFD1 P11586 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 Enzyme 4.5E-03 0.554 0.769 17
CD3E P07766 CD3e molecule 3.4E-04 0.615 0.615 21
CD3D P04234 CD3d molecule 8.6E-05 0.626 0.577 22
LEP P41159 leptin 0.46 0.349 0.846 25
FCGR2A P12318 Fc fragment of IgG receptor IIa Cell adhesion 2.0E-06 0.480 0.769 28
CD247 P20963 CD247 molecule 1.7E-02 0.539 0.731 29
P4HTM Q9NXG6 prolyl 4-hydroxylase, transmembrane 3.9E-09 0.666 0.500 30
JAK3 P52333 Janus kinase 3 Kinase 5.9E-06 0.505 0.731 32
IGLL1 P15814 immunoglobulin lambda like polypeptide 1 1.4E-02 0.678 0.538 34
CD19 P15391 CD19 molecule 0.90 0.430 0.885 35
TNFRSF13C Q96RJ3 TNF receptor superfamily member 13C 0.27 0.540 0.731 35
BLNK Q8WV28 B cell linker Signaling 0.61 0.603 0.731 36
CXCR4 P61073 C-X-C motif chemokine receptor 4 G-protein coupled receptor 1.8E-02 0.362 0.923 36
ICOS Q9Y6W8 inducible T cell costimulator 3.1E-02 0.502 0.731 36
CD79B P40259 CD79b molecule Receptor 0.92 0.576 0.577 37
CR2 P20023 complement C3d receptor 2 4.7E-19 0.556 0.654 37
TNFRSF13B O14836 TNF receptor superfamily member 13B 2.1E-15 0.558 0.769 38
GAS8 O95995 growth arrest specific 8 1.1E-12 0.636 0.654 39
IGHM P01871 immunoglobulin heavy constant mu 0.644 0.654 39
NCF1 P14598 neutrophil cytosolic factor 1 2.8E-05 0.521 0.808 41