Source: INFERRED

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885 59
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846 342
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923 382
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923 133
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923 67
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923 62
COX2 P00403 cytochrome c oxidase subunit II Enzyme 0.352 0.962 137
NLRP3 Q96P20 NLR family pyrin domain containing 3 8.1E-04 0.361 0.962 112
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885 330
TP63 Q9H3D4 tumor protein p63 Transcription factor 1.00 0.362 0.769 266
CTLA4 P16410 cytotoxic T-lymphocyte associated protein 4 0.94 0.369 0.923 122
FAS P25445 Fas cell surface death receptor 0.81 0.372 0.923 168
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808 381
MET P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 0.97 0.380 0.846 19
LMNA P02545 lamin A/C 1.00 0.384 0.885 468
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923 286
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808 216
FGFR3 P22607 fibroblast growth factor receptor 3 Kinase 1.6E-05 0.391 0.846 307
RET P07949 ret proto-oncogene Kinase 1.00 0.392 0.885 170
GJA1 P17302 gap junction protein alpha 1 Cell-cell junction 0.16 0.393 0.885 224
TWIST1 Q15672 twist family bHLH transcription factor 1 Transcription factor 0.34 0.397 0.846 125
COX8A P10176 cytochrome c oxidase subunit 8A Enzyme 0.12 0.400 0.846 38
SOX2 P48431 SRY-box transcription factor 2 Transcription factor 0.71 0.405 0.808 79
DNMT1 P26358 DNA methyltransferase 1 Epigenetic regulator 1.00 0.406 0.885 60